At extremes of scale, organisations often move to binary protocols - for example. Systems using these still exhibit the characteristic of smart endpoints, dumb pipes - and trade off for scale. Most web properties and certainly the vast majority of enterprises don't need to make this tradeoff - transparency can be a big win.
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Taken together, these findings indicate that in obese persons who have lost weight, multiple compensatory mechanisms encouraging weight gain, which persist for at least 1 year, must be overcome in order to maintain weight loss. These mechanisms would be advantageous for a lean person in an environment where food was scarce, but in an environment in which energy-dense food is abundant and physical activity is largely unnecessary, the high rate of relapse after weight loss is not surprising. Furthermore, the activation of this coordinated response in people who remain obese after weight loss supports the view that there is an elevated body-weight set point in obese persons and that efforts to reduce weight below this point are vigorously resisted. In keeping with this theory, studies have shown that after adjustment for body composition, people whose weight is normal and those who are obese have similar energy requirements for weight maintenance and equivalent reductions in energy expenditure after weight loss. If this is the case, successful management of obesity will require the development of safe, effective, long-term treatments to counteract these compensatory mechanisms and reduce appetite. Given the number of alterations in appetite-regulating mechanisms that have been described so far, a combination of medications will probably be required. Several such combinations are undergoing evaluation, but none have been approved by the Food and Drug Administration. Bariatric surgery has well-documented favorable effects on appetite-mediating hormones, hunger, body weight, hypertension, dyslipidemia, type 2 diabetes, and mortality. However, because of the attendant costs and long waiting periods, bariatric surgery is not readily accessible to most people.
A research paper is not simply an informed summary of a topic by means of primary and secondary sources. It is neither a book report nor an opinion piece nor an expository essay consisting solely of one's interpretation of a text nor an overview of a particular topic. Instead, it is a genre that requires one to spend time investigating and evaluating sources with the intent to offer interpretations of the texts, and not unconscious regurgitations of those sources. The goal of a research paper is not to inform the reader what others have to say about a topic, but to draw on what others have to say about a topic and engage the sources in order to thoughtfully offer a unique perspective on the issue at hand. This is accomplished through two major types of research papers.
Becoming an experienced researcher and writer in any field or discipline takes a great deal of practice. There are few individuals for whom this process comes naturally. Remember, even the most seasoned academic veterans have had to learn how to write a research paper at some point in their career. Therefore, with diligence, organization, practice, a willingness to learn (and to make mistakes!), and, perhaps most important of all, patience, a student will find that she can achieve great things through her research and writing.