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Research Paper Diabetes - 2770 Words

Epidemiological studies also support a relationship between sleep disturbances and diabetes. In 2010, Cappuccio et al. conducted a meta-analyses of 10 prospective epidemiological studies that investigated the relationship between quantity and quality of sleep and the incidence of type 2 diabetes (). Their analysis of a total combined study sample of > 100,000 participants and 3,586 incident cases indicated that both the quality and quantity of sleep consistently and significantly predicted the risk of type 2 diabetes.

### Additional study authors include Giuseppina Imperatore, MD, PhD, of the Division of Diabetes Translation, Centers for Disease Control and Prevention; Dana Dabelea, MD, PhD, of the Department of Epidemiology, Colorado School of Public Health, University of Colorado Denver; Elizabeth J. Mayer-Davis, PhD, of the Department of Nutrition, Gillings School of Global Public Health, University of North Carolina and School of Medicine, University of North Carolina; Barbara Linder, MD, PhD, of the National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health; Sharon Saydah, PhD, of the Division of Diabetes Translation, Centers for Disease Control and Prevention; Georgeanna J. Klingensmith, MD, of the Division of Diabetes Translation, Centers for Disease Control and Prevention, Atlanta; Lawrence Dolan, MD, of the Division of Endocrinology, Cincinnati Children's Hospital Medical Center and Department of Pediatrics, University of Cincinnati; Debra A. Standiford, MSN, CNP, of the Division of Endocrinology, Cincinnati Children's Hospital Medical Center; Catherine Pihoker, MD, of the Department of Pediatrics, University of Washington, Seattle; David J. Pettitt, MD, of the Sansum Diabetes Research Institute; Jennifer W. Talton, MS, of the Department of Biostatistical Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina; Joan Thomas, MS, RD, of the Department of Nutrition, Gillings School of Global Public Health, University of North Carolina, Chapel Hill; Ronny A. Ball, PhD, of the Department of Epidemiology and Prevention, Wake Forest School of Medicine; and Ralph B. D'Agostino, Jr., of the Department of Biostatistical Sciences, Wake Forest School of Medicine, for the SEARCH For Diabetes in Youth Study Group. About the Kaiser Permanente Southern California Department of Research & Evaluation The Department of Research & Evaluation conducts high-quality, innovative research into disease etiology, prevention, treatment and care delivery. Investigators conduct epidemiology, health sciences and behavioral research as well as clinical trials. Areas of interest include diabetes and obesity, cancer, HIV/AIDS, cardiovascular disease, aging and cognition, pregnancy outcomes, women's and children's health, quality and safety, and pharmacoepidemiology. Located in Pasadena, California, the department focuses on translating research to practice quickly to benefit the health and lives of Kaiser Permanente Southern California members and the general population. About Kaiser Permanente Kaiser Permanente is committed to helping shape the future of health care. We are recognized as one of America's leading health care providers and not-for-profit health plans. Founded in 1945, our mission is to provide high-quality, affordable health care services and to improve the health of our members and the communities we serve. We currently serve approximately 9.3 million members in 8 states and the District of Columbia. Care for members and patients is focused on their total health and guided by their personal physicians, specialists and team of caregivers. Our expert and caring medical teams are empowered and supported by industry-leading technology advances and tools for health promotion, disease prevention, state-of-the-art care delivery and world-class chronic disease management. Kaiser Permanente is dedicated to care innovations, clinical research, health education and the support of community health.

There is a growing number of Hispanic being diagnosed with type 2 diabetes.

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Type 2 diabetes, in Hispanic should be addressed because the disease can be prevented.

Identification of outcome. Incident diabetes cases diagnosed between baseline and death, emigration, or the end of follow-up (27 June 2006) were identified by linking the unique personal identification number of each cohort member to the Danish National Diabetes Registry (NDR) (). The NDR was established in 2006 by the National Board of Health by linking the following nationwide registries and data: the National Hospital Registry, for hospital discharge diagnoses since 1977; the National Health Insurance Registry, for information on all services provided by general and specialist practitioners since 1973; and the Register of Medicinal Product Statistics, for information on all prescriptions dispensed at Danish pharmacies since 1993. Inclusion criteria for the NDR were as follows: a hospital discharge diagnosis of diabetes in the National Patient Register {International Classification of Diseases, 10th Revision [ICD-10; ]: DE10–14, DH36.0 and DO24}; National Health Insurance Registry information indicating podiatry (chiropody) for diabetic patients, five blood glucose measurements within 1 year, or two blood glucose measurements per year for 5 consecutive years; or > 1 purchase of insulin or oral glucose-lowering drugs within 6 months registered in the Register of Medicinal Product Statistics. The registry has been reported to have a positive predictive value of 89% (). Among the 3,869 cases in the present study 55% met more than one inclusion criterion. The date of inclusion into the NDR has been found to be well defined only for persons entering after 1 January 1995 (), so the incidence of diabetes is defined as the date of the earliest record in the NDR after 1 January 1995 and before 27 June 2006. Participants were excluded from the present analysis if they were diagnosed with diabetes before 1995, or were diagnosed before baseline if enrolled after 1995. In addition, we excluded participants diagnosed with cancer before baseline. We also applied a stricter incidence definition by excluding individuals registered in the NDR solely because of a history of blood glucose tests.

While long-term complications are rare in childhood, maintaining good control of diabetes is important to prevent complications from developing in later life.

Diabetes - Free Essays, Term Papers, Research Paper, …

Diabetes mellitus and its associated macrovascular (; ) and microvascular () complications constitute a serious threat to global human health and welfare (). The burden of diabetes relates particularly to type 2 diabetes, which accounts for 90–95% of cases globally (). Although obesity (), diet (), and physical inactivity () have been identified as important risk factors for type 2 diabetes, there is increasing evidence that insulin resistance, the underlying hallmark and pathophysiological mechanism leading to type 2 diabetes, can be aggravated by factors that promote inflammatory responses ().

- Cleft Palate research papers examine the congenital deformity that occurs during gestation.

Until now research on traffic noise has focused on cardiovascular effects, although given the putative mechanisms of action, traffic noise might also contribute to type 2 diabetes. First, excess of glucocorticoids, as seen in Cushing syndrome, have been found to inhibit insulin secretion by pancreatic β cells and reduce insulin sensitivity in liver, skeletal muscle, and adipose tissue (), as well as increase the risk of diabetes (; ). Second, experimental reduction in the duration or quality of sleep in human volunteers has been associated with alterations in glucose regulation including a drop in glucose tolerance (), increased morning levels of glucose, and decreased levels of insulin () and reduced insulin sensitivity (). Slow-wave sleep, which is associated with inhibition of cortisol secretion, decreased sympathetic nervous system activity, increased vagal tone, and stimulation of growth hormone release, is especially important for glucose regulation (). A 90% reduction in slow-wave sleep caused by acoustic stimuli has been associated with decreased glucose tolerance and reduced insulin sensitivity (; ). Third, hormones responsible for appetite regulation have been found to be affected by sleep reduction, with decreased leptin levels and elevated ghrelin levels resulting in up-regulation of appetite, which in turn may result in higher body mass index (BMI) and an increased risk of diabetes (; ).

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# Research Paper On Diabetes ★★★ Diabetes Care …


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In the last decade, showed that for people suffering from type 2 diabetes, a low-fat plant-based diet can improve glycemic control and reduce the need for medication. While we have since seen an often reporting of these claims, many are still left wondering if the science is real, and just how much a dietary change really could affect diabetes.

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Recent research has shown that some long-term damage to the body, especially the heart and circulatory system, may already be occurring during pre-diabetes.

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It is only recently that ambient air pollution has been implicated in the etiology of type 2 diabetes (). Exposure to air pollution has been associated with cardiovascular-related mortality and morbidity (; ). There is also evidence that persons with diabetes are particularly susceptible to the acute effects of air pollution (; ). In a mouse model, exposure to fine particulate matter (particles with an aerodynamic diameter ≤ 2.5 µm; PM2.5) increased blood glucose and induced adipose inflammation and insulin resistance (). This animal study provides a potential biological basis for the link between air pollution and diabetes.

type 2 diabetes and gestational diabetes

- Metabolic Syndrome research papers examine the medical disorder characterized by at least three of the five following symptoms: abdominal obesity, elevated blood pressure, elevated fasting glucose, high triglycerides, and low HDL cholesterol levels.

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The SEARCH for Diabetes in Youth study is a national multicenter study aimed at developing a deeper understanding of type 1 and type 2 diabetes among children and adolescents in the United States. The study, which started in 2000, involves centers located in five states -- California, Colorado, Ohio, South Carolina and Washington -- and is funded by the Centers for Disease Control and Prevention and the National Institute of Diabetes and Digestive and Kidney Diseases.

Diabetes is the long term disease which have been controlled but …

While there are several studies indicating the benefits of a plant-based diet, there is no definite consensus on why or how these benefits work. A very popular opinion is that vegans consume less fat, including both saturated and total fat consumption. This leads to a reduced caloric intake and hence weight loss. Type 2 diabetes is ; in fact, obese people have a seven times higher risk of developing the disease.

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Citation: Sørensen M, Andersen ZJ, Nordsborg RB, Becker T, Tjønneland A, Overvad K, Raaschou-Nielsen O. 2013. Long-Term Exposure to Road Traffic Noise and Incident Diabetes: A Cohort Study. Environ Health Perspect 121:217–222;

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